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The project
Plasmonic nanostructures with applications in biophotonics will explore the unique physical-chemical and
biological properties of noble-metal nanoparticles and
nanostructures: (1) optical properties defined by plasmonic
resonances, (2) chemical affinity toward some (bio)molecules and (3)
bio-compatibility and non toxicity.
Firstly, we will fabricate gold nanoparticles with controlled size
(10-100 nm) and shape (spheres, roads, triangles) and will study
plasmonic resonances of this nanoparticles self-assembled on solid
substrates or inserted in biopolymer matrix and biomimics media.
Secondly, we will develop some applications for ultra sensitive
spectroscopic analysis in order to detect in vitro some molecular
systems and bio nanostructures through SERS, LSPR, SEIRA and
fluorescence, including intracellular plasmonics imaging. Then, we
will explore the biophotonics bases of new procedures for tumors
nanodiagnose and photothermic therapy.
This research will integrate experimental measurements obtained by
confocal Raman, atomic force microscopy imaging (AFM) and optical
microscopy imaging with theoretical results obtained by
computational methods of physical-chemistry property of some
nanostructured materials and molecules. The project will allow the
build-up qualified human resources for research activity by opening
3 full-time doctoral and post-doctoral positions.
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